Biotech Basics

Biotech Basics is an ongoing series developed by Dr. Neil Lamb, director of educational outreach for the HudsonAlpha Institute for Biotechnology. Each lesson is designed to help each of us understand biotechnology basics and the tools and technologies that improve quality of life.

Stem Cells

Edition: 
Summer 2011
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What you need to know:

Psychiatric Disorders

Edition: 
Spring 2011
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What you need to know:

2010: end-of-year review

Edition: 
Winter 2010-11
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This Biotech Basics is an assembly of the most important findings of 2010. These findings were originally published in the Biotechnology Discoveries and Applications guidebook, an easy-to-use resource that keeps life science educators and their students on the cutting edge. Research highlights in this article are culled from the eight-page New Findings section of the guidebook, summarizing major discoveries from the past twelve months. For links to more information about each new finding, visit the guidebook online (see link at end of article).

Metabolomics

Edition: 
Fall 2010
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What You Need to Know

Synthetic Biology - merging engineering and biology

Edition: 
Summer 2010
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What you need to know:

Unlocking the Disorders of the Mind

Edition: 
Spring 2010
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What you need to know:

Telomeres - the aglets of the genomic world

Edition: 
Winter 2009-10
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What you need to know:

  • DNA is organized into small structures known as chromosomes. At the ends of each chromosome are repeating sequences of DNA known as telomeres.

The Genetics of Eye Color

Edition: 
Fall 2009
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Countless students have been taught that a single gene controls eye color, with the allele for brown eyes being dominant over blue. Scientists now realize such a model is overly simplistic and incorrect.

2009 H1N1 Flu Outbreak

Edition: 
Summer 2009
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2009 H1N1 Flu Outbreak:  separating myth from fact

Note: this edition of Biotech101 represents a departure from our traditional article style. Instead, we’ll be exploring details about the H1N1 virus in a “question and answer” format.

Genome-wide Association Studies

Edition: 
Spring 2009
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Searching for genetic needles in haystacks of data

Comparative Genomics

Edition: 
Winter 2008-09
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Comparative Genomics - What you need to know

Cancer

Edition: 
Fall 2008
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Cancer - What you need to know

Copy Number Variation

Edition: 
Summer 2008
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Copy Number Variation - Another way the genetic recipe differs

The Human Genome Project

Edition: 
Spring 2008
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The Human Genome Project: looking back, looking ahead

Personalized Medicine

Edition: 
Winter 2007
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Personalized Medicine - What you need to know

Epigenetics

Edition: 
Fall 2007
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Epigenetics: Flipping the genetic "switch"

Recent discoveries have shed light on how genes alternate between silent and active states. These activity patterns appear to be susceptible to environmental influences, with serious health consequences that stretch across generations.

DNA Microarrays

Edition: 
Spring 2007
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DNA Microarray - Studying activity of genes

“The ability of an organism to live and function depends upon the activity of thousands of genes and the complex interaction between those genes and the proteins they produce. A powerful laboratory tool, a DNA microarray, provides a glimpse into this world of genetic interactions by distinguishing cells based on the activity of their genes.”

RNAi

Edition: 
Winter 2006-07
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RNAi - understanding the process

Much like turning off a light switch, RNA interference (RNAi) offers the ability to selectively silence or “turn off” the activity of a single gene. This technology has the potential to revolutionize our understanding of how genes work and offers new promise in therapy and treatment.